Isotopically Labeled Compounds
Medchemexpress LLC Ethylmalonic acid-d3 | 70907-93-6 | 98.0% | 135.13 | 1 MG
Ethylmalonic acid-d3 is the deuterium labeled Ethylmalonic acid. It is a short-chain organic dicarboxylic acid that synergistically induces mitochondrial permeability transition (MP) with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. It can be used in the research of SCADD, EE, and other genetic metabolic diseases characterized by EMA accumulation.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Dimethyl fumarate-d2 | 23057-98-9 | MFCD08704934 | 99.2% | 146.14 g/mol | C6H6D2O4 | 10 MG
Dimethyl fumarate-d2 is the deuterium-labeled isotopologue of dimethyl fumarate provided as a research reference standard. It is used in analytical, pharmacokinetic, and mechanistic studies where a mass-shifted tracer or internal standard is required, enabling precise detection and quantitation by mass spectrometry.
- Deuterium-labeled for mass spectrometry and tracer studies.
- Suitable as an internal standard in analytical and pharmacokinetic assays.
- High chemical purity: 99.2%.
- Available in small research quantities (10 mg) for analytical workflows.
- Molecular formula C6H6D2O4; molecular weight 146.14 g/mol.
Medchemexpress LLC Atrazine-d5 | 163165-75-1 | 5 MG
Atrazine-d5 is deuterium labeled Atrazine. Atrazine is primarily used for controlling certain annual broadleaf and grass weeds. It inhibits photophosphorylation but typically does not cause lethality or permanent cell damage in the short term.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Molecular weight: 220.71
- Formula: C8H9D5ClN5
- Appearance: Solid
- Color: White to off-white
- Purity: 98.72%
Cayman Chemical Carbofurn-d3 1mg
An internal standard for the quantification of carbofuran by GC-or LC-MS
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphorylcholine-d13 | 803.23 g/mol | C44H75D13NO8P | 1 MG
DSPC-d13 (1,2-distearoyl-sn-glycero-3-phosphorylcholine-d13) is a deuterium-labeled phospholipid used as a tracer and analytical standard and as a lipid component in liposome and lipid nanoparticle formulations.
- Deuterium labeled (D13), contains 13 deuterium atoms.
- Molecular weight 803.23 g/mol.
- Molecular formula C44H75D13NO8P.
- Available as a 1 mg sample.
- Typical applications include liposome and lipid nanoparticle formulation, tracer studies, and mass spectrometry internal standards.
Medchemexpress LLC L-ornithine-d6 hydrochloride | 347841-40-1 | >98.0% | 174.66 g/mol | C5H7D6ClN2O2 | 10 MG
L-Ornithine-d6 hydrochloride is the deuterium-labeled form of L-ornithine supplied as the monohydrochloride salt. It is intended for use as an isotope-labeled reference standard in metabolomics, mass spectrometry, and quantitative analytical workflows where a labeled internal standard or tracer is required.
- Deuterium-labeled (d6) analog for isotope dilution workflows.
- Provided as the monohydrochloride salt for stability and solubility.
- Typical isotopic enrichment ≥98 atom % D.
- Chemical purity ≥98%.
- Molecular weight 174.66 g/mol.
- Suitable as an internal standard for LC-MS and GC-MS assays.
Medchemexpress LLC (Rac)-Cotinine-d3 | 110952-70-0 | 99.0% | 1 MG
(Rac)-Cotinine-d3 is a deuterium-labeled form of (Rac)-Cotinine. This compound is used for research purposes, including as a tracer and an internal standard for quantitative analysis. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules as tracers during drug development, which can impact their pharmacokinetic and metabolic profiles.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation
- Potential to affect pharmacokinetic and metabolic profiles of drugs through deuteration
Medchemexpress LLC Nonanoyl-CoA-d17 | >98.0% | 924.86 | C30H35D17N7O17P3S | 1mg
Nonanoyl-CoA-d17 (Pelargonoyl-CoA-d17) is the deuterium labeled Nonanoyl-CoA (HY-E70246) Nonanoyl-CoA is a medium-chain fatty acyl-CoA that can be used as substrate for the medium-chain hydrolase[1]
Medchemexpress LLC L-tryptophan-15N2 | 204634-20-8 | MFCD00209799 | 99.9% | 206.21 | C11H12(15N)2O2 | 10 MG
L-Tryptophan-15N2 is the nitrogen-15 doubly labeled form of the essential amino acid L-tryptophan, supplied as a white to off-white solid for use as a tracer or internal standard in quantitative NMR, GC-MS, and LC-MS analyses and metabolic flux studies.
- Isotope-labeled (15N2) for tracer and internal standard applications.
- High purity - 99.9% suitable for analytical workflows.
- Supplied as a stable solid for convenient storage and handling.
- Recommended storage: 4°C protected from light; in solution: -80°C (6 months), -20°C (1 month).
- Compatible with NMR, GC-MS, and LC-MS quantitative assays.
Medchemexpress LLC Methyl palmitate-13C16 | 112-39-0 | 99.8% | 286.33 | C13C16H34O2 | 10 MG
Methyl palmitate-13C16 is a 13C-labeled isotopologue of methyl palmitate supplied as a high-purity stable-isotope reference for analytical workflows and mass spectrometry. It is intended for use as an internal standard to improve quantitation and peak identification in LC-MS and GC-MS analyses.
- 13C16-labeled isotopologue for isotope-dilution quantitation.
- High purity: 99.8%.
- Molecular formula C13C16H34O2; molecular weight 286.33 g/mol.
- Available in small preweighed quantities, including 10 MG.
- Suitable as an internal standard for mass spectrometry analyses.
Medchemexpress LLC Ercalcidiol-d3 | 1217467-39-4 | 99.9% | 415.67 | 100 UG
Ercalcidiol-d3 is the deuterium labeled Ercalcidiol, a metabolite of Vitamins D2. It serves as an indicator of vitamin D status and can be utilized as a tracer and internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS. Stable heavy isotopes, including hydrogen and carbon, are incorporated into this drug molecule. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as an indicator of vitamin D status.
- Functions as a tracer in quantitative analysis.
- Serves as an internal standard for NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Mavacamten-d7 | 1642288-47-8 | 99.7% | 280.37 | 50 MG
Mavacamten-d7 (MYK461-d7) is a deuterium labeled variant of Mavacamten. Mavacamten is an orally active modulator of cardiac myosin, with IC50s of 490 nM and 711 nM for bovine cardiac and human cardiac, respectively.
- Deuterium labeled compound
- Modulator of cardiac myosin
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Hydroxylamine-d3 hydrochloride | 15588-23-5 | MFCD00075189 | 99.0% | 72.51 | ClHD3NO | 100mg
Hydroxylamine-d3 (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms such as ammonium oxidizing bacteria (AOB) ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox) Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity[1][2][3]
Cayman Chemical SalIcylIc AcId-d4 5mg
An internal standard for the quantification of salicylic acid by GC- or LC-MS
Cayman Chemical FK-506-13C-d2 500ug
An internal standard for the quantification of FK-506 by GC- or LC-MS